The study enrolled a total of 21 patients, of whom 11 in the experimental group and 10 in the control group. Before the beginning of the procedure (a venipuncture for blood sample), behavioural distress did not appear to be different in the two groups (6.2 vs. 10.3), as well as the fear perceived by the child and anxiety. 30 seconds after the start of the VR (Virtual Reality) video, behavioural distress was significantly lower in the experimental group (0.1 vs. 8.9, p 0.018), as well as the pain expressed by the child (0.6 vs 4.1, p 0.013) and the pain perceived by the child evaluated by the parent (0.7 vs 3.44, p 0.018). This study supports the effectiveness of VR as a distraction technique in patients with FC who frequently have to face invasive procedures.