STRATEGIC PROJECTS

Strategic Projects

Strategic projects are initiatives that the Foundation launches in a more targeted and detailed manner, with the aim of promoting promising scientific research and raising public awareness about the issues related to cystic fibrosis:

Molecules 3.0 for Cystic Fibrosis – New pharmacological modulators for the recovery of the mutated CFTR protein. Phase 1 – Phase 2 – Phase 3 – Phase 4 – Phase 5

Kaftrio in Real Life – Effectiveness and safety of Kaftrio in real life: an Italian observational and multicenter study. Phase 1 – Phase 2

1 in 30 and You Don’t Know It – Awareness project on the carrier testing for cystic fibrosis. Phase 1 – Phase 2 – Phase 3 – Phase 4

Task Force for Cystic Fibrosis – New and more effective correctors of the mutated CFTR protein

Experts Together – Improving integration and alignment of goals between the CF community and the world of science and research

GenDel-CF – Gene transfer strategies in the lungs for the treatment of cystic fibrosis

MindKids-CF – Study on mental health in children with cystic fibrosis

De-risking GY – Assessing the safety and clinical potential of GY971, an anti-inflammatory compound for cystic fibrosis

Over 40 – Multicentre observational study of the Italian population with cystic fibrosis aged 40 years and older

Restart-CFTR – Overcoming nonsense mutation to restore CFTR protein

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FFC Ricerca 2026-2030 strategic project: Restart-CFTR

A new strategy based on ACE-tRNAs and their targeted delivery to airway cells
€ 1.584.428 funds raised
0%
€ 1.584.428
Goal

FFC Ricerca 2026-2027 strategic project: Over 40

Multicentre observational study of the Italian population with cystic fibrosis aged 40 years and older
€ 19.015 funds raised
0%
€ 19.015
Goal

FFC Ricerca 2025 strategic project: De-risking GY

Assessing the safety and clinical potential of GY971, an anti-inflammatory compound for cystic fibrosis
€ 115.812 funds raised
0%
€ 115.812
Goal

FFC Ricerca 2025-2028 strategic project: MindKids-CF

Development of screening and monitoring tools for anxiety, depression, and behavior Problems in Italian Children with Cystic Fibrosis under 12 Years of Age
€ 169.596 funds raised
0%
€ 169.596
Goal

FFC Ricerca 2025 strategic project: 1 in 30 and you don’t know it. Phase 4

An information and awareness campaign on the test of the healthy carrier of cystic fibrosis.
€ - funds raised
0%
€ 180.000
Goal

FFC Ricerca 2024-2027 Strategic Project: GenDel-CF

Tackling gene delivery in lungs for the treatment of cystic fibrosis.
€ 110.207 € funds raised
0%
€ 1.870.207 €
Goal

FFC Ricerca 2024-2025 Strategic Project: Molecules 3.0 for CF. Phase 5

Advanced functional validation of CFTR new modulators and selection of lead candidates for further development
€ 149.100 funds raised
0%
€ 149.100
Goal

FFC Ricerca 2023-2025 Strategic Project: Kaftrio in real life

Efficacy and safety of Kaftrio in real life: an observational multicenter Italian clinical study involving people with CF who received the drug through the compassionate use program and after AIFA approval.
€ - funds raised
0%
€ 150.000
Goal

FFC Ricerca 2026 Strategic Project: Experts together for Andrea (3rd year)

Inclusion and activation of CF Community as partners in the various stages of the research process
€ 19.817 funds raised
0%
€ 19.817
Goal