Developed skills and lines of research
Since 2016, Marco Scocchi has been an Associate Professor of Biochemistry (BIO/10) at the Department of Life Sciences, University of Trieste, having obtained his PhD in Biochemistry in 1997. He is a member of the Italian Society of Biochemistry and Molecular Biology (SIB), the European Peptide Society, and the American Society of Microbiology. His research interests concern the study of the mechanisms of innate immune defenses based on host defense peptides, i.e., the so-called antimicrobial peptides or AMPs, which the Researcher is imitating with synthetic molecules, usable in the treatment of Ps. aeruginosa infection in cystic fibrosis.
Projects funded by FFC Ricerca as Principal Investigator or as Research Manager
FFC#14/2014
Development of BMAP18 as a peptide drug in the lung bacterial infections: a study to improve its effectiveness in the CF pulmonary environment
FFC#11/2012
Development of optimized anti-infective peptides and exploration of a novel drug delivery system for the respiratory infection therapy in an animal model
Publications from FFC Research projects
Mardirossian M, Pompilio A, Degasperi M, et al. D-BMAP18 Antimicrobial Peptide Is Active In vitro, Resists to Pulmonary Proteases but Loses Its Activity in a Murine Model of Pseudomonas aeruginosa Lung Infection. Front Chem. 2017 Jun 19;5:40. doi: 10.3389/fchem.2017.00040. eCollection 2017.