Developed skills and lines of research

Giovanni Marzaro is professor at the Department of Pharmaceutical Sciences (DSF) at the University of Padua. He earned his degree in Chemistry and Pharmaceutical Technology in 2005 and his Ph.D. in Molecular Sciences in 2009 at the University of Padua.
His primary research interests include the rational design and synthesis of small organic molecules with biological activity (CFTR modulators, potential anti-tumor agents, potential anti-infectives). His research activities encompass computational chemistry studies (simulation of drug/target molecular interactions) and the synthetic preparation of molecules identified through computational studies.
For FFC Ricerca, Giovanni Marzaro is involved in developing new CFTR correctors and potentiators in collaboration with Prof. Gergely Lukacs’s research group at McGill University (Canada), with a focus on molecules targeting rare CFTR mutations.
In the past, he contributed to the development of GY971, a new coumarin-based anti-inflammatory drug currently undergoing orphan drug designation evaluation by the European Medicines Agency (EMA).
He has participated as a collaborator in FFC Ricerca projects FFC#8/2014, FFC#1/2016, and FFC#22/2019.
He is the author or co-author of 66 articles in peer-reviewed scientific journals and the inventor of a patent.

Projects funded by FFC Ricerca as Principal Investigator

FFC#1/2024
Development of new potentiators active on (ultra)rare mutants of CFTR