Developed skills and lines of research

Maria Lleò earned her PhD in Biological Sciences from the Complutense University of Madrid (Spain) in 1979 and from the University of Genoa (Italy) in 1985. She is currently an Associate Professor of Microbiology and Clinical Microbiology at the University of Verona, School of Medicine. Since 1992, Lleò has coordinated the Diagnostic Microbiology Service at the University Hospital of Verona. In the field of CF, she is studying the anti-inflammatory and antibacterial activity of new compounds in a special transgenic CF mouse model.

Projects funded by FFC Ricerca as Principal Investigator or as Research Manager

FFC#18/2019
Investigating Achromobacter xylosoxidans pathogenicity and clinical role in CF lung infection

FFC#10/2015
A CF, IL-8 transgenic mouse model for the in vivo, long-term monitoring of the anti-inflammatory role of metallo-protease inhibitors and antibiotics with mechanisms of action similar to that of azithromycin

FFC#18/2013
Development of a CF, IL-8/NF-KB transgenic mouse model for the in vivo long-term monitoring of the inflammatory response induced by bacteria treated or not with azithromycin

Publications from FFC Research projects

Stellari F, Bergamini G, Sandri A, et al. In vivo imaging of the lung inflammatory response to Pseudomonas aeruginosa and its modulation by azithromycin. J Transl Med, 2015 Aug 4;13:251. doi: 10.1186/s12967-015-0615-9.

Sandri A, Ortombina A, Boschi F, et al., Inhibition of Pseudomonas aeruginosa secreted virulence factors reduces lung inflammation in CF mice. Virulence. 2018;9(1):1008-1018. doi: 10.1080/21505594.2018.1489198.