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Galietta Luis

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Galietta Luis

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Università degli Studi di Napoli Federico II – Istituto Telethon di Genetica e Medicina TIGEM, Pozzuoli, Napoli

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Developed skills and lines of research

Born in Caracas, Venezuela, in 1959, Luis Galietta graduated in Biological Sciences from Federico II University of Naples. He began his research career with a fellowship from the Giannina Gaslini Institute in Genoa. After several experiences in the United States, he returned to Italy. Galietta spent many years as a researcher and senior scientist at the Molecular Genetics Laboratory of the Giannina Gaslini Institute. Since 2017, he has conducted research at the Telethon Institute of Genetics and Medicine (TIGEM) in Pozzuoli (Naples), in close collaboration with the Giannina Gaslini Institute. Since 2018, he has been an Associate Professor of Medical Genetics at Federico II University of Naples.

His work has included studying ion channels in human fibroblasts and keratocytes at the Gaslini Institute and the Institute of Cybernetics and Biophysics (CNR). He has also worked on the development of novel fluorescent proteins to study ion channels and transporters. He is actively involved in high-throughput screening of chemical compounds to identify pharmacological modulators of the CFTR protein. He has served as the coordinator and now co-leader of the strategic project Task Force for Cystic Fibrosis (TFCF) in collaboration with the Italian Institute of Technology (IIT) in Genoa.

He has published over 200 papers in international journals.

Projects funded by FFC Ricerca as Principal Investigator or as Research Manager

FFC#9/2022
Effect of inflammatory stimuli on airway epithelium ion transport in cystic fibrosis

FFC Research strategic project 2021-2023. Molecules 3.0 for cystic fibrosis. Phase 2 New pharmacological modulators for the recovery of mutated CFTR protein

FFC#6/2019
Identification of deubiquitinases and ubiquitin ligases that affect mutant CFTR rescue

FFC#2/2017
Identification of deubiquitinases and ubiquitin ligases that affect mutant CFTR rescue

FFC/TFCF 3ª fase
Task Force for Cystic Fibrosis

FFC/TFCF 2ª fase
Task Force for Cystic Fibrosis

FFC/TFCF 1ª fase
Task Force for Cystic Fibrosis

FFC#2/2012
Development of novel strategies to correct the chloride transport defect in cystic fibrosis

FFC#2/2009
Development of small molecules to correct the defective chloride transport in cystic fibrosis

FFC#3/2006
Identification, optimization, and validation of potentiators and correctors for the pharmacotherapy of cystic fibrosis

FFC#3/2003
Screening of drugs approved for human use to identify novel pharmacological tools for cystic fibrosis


Projects financed by FFC Ricerca as a partner

FFC/TFCF fase preclinica
Task Force for Cystic Fibrosis

FFC #3/2007
Computational design, biochemical study, synthesis and screening of pharmacological chaperones as correctors of ΔF508-CFTR

Publications from FFC Research projects