Maurizio Fraziano graduated in Biological Sciences from La Sapienza University of Rome in 1992 and obtained his PhD in Cytodifferentiation and Morphogenesis in 1996. Since 2001, he has taught various courses, including Immunotechnology, Immunology, Molecular Basis of Cellular Response to Infections, Immunology and Pathology, and Applied Immunology.
He has been a university researcher at the Department of Biology, University of Rome Tor Vergata, since 2001. His scientific output includes over 40 indexed publications and two patents. For the Italian Cystic Fibrosis Foundation (FFC Ricerca), he is studying a new antibacterial aerosol based on specialized liposomes (lipid particles) that enhance natural immune defenses. Since 2015, he has been an Associate Professor of Medical Microbiology at the Department of Biology, School of Sciences, University of Rome Tor Vergata.
Projects funded by FFC Ricerca as Principal Investigator
FFC#13/2022
Fighting Mycobacterium abscessus infections by a novel combination therapy
FFC#21/2019
Studio preclinico di una strategia terapeutica combinata basata su liposomi bioattivi e batteriofagi contro le infezioni causate da Mycobacterium abscessus
FFC#14/2017
Preclinical study of a combined host- and pathogen directed approach based on bioactive liposomes and bacteriophages against Mycobacterium abscessus infection
FFC#17/2013
Preclinical study of a novel aerosol immunotherapeutic approach based on Janus-faced liposomes to enhance innate antimicrobial immunity
Publications from FFC Research projects
- Poerio N, Bugli F, Taus F et al. Liposomes loaded with bioactive lipids enhance antibacterial innate immunity irrespective of drug resistance. Sci Rep. 2017 Mar 27;7:45120. doi: 10.1038/srep45120.
- Nisini R, Poerio N, Mariotti S, et al., The Multirole of Liposomes in Therapy and Prevention of Infectious Diseases. Front Immunol. 2018 Feb 5;9:155. doi: 10.3389/fimmu.2018.00155. eCollection 2018.
- Noemi Poerio, Federica De Santis, Alice Rossi, Ana Henriquez, Federica Di Sano, Vincenzina Lucidi, Alessandra Bragonzi, Maurizio Fraziano. Preclinical study of a host-directed therapy based on Metformin and bioactive liposomes for the control of multidrug resistant P. aeruginosa infection. The Proceedings of the 16th Italian Convention of Investigators in Cystic Fibrosis. Multidisciplinary Respiratory Medicine, 2019, 14 (Suppl 1):5