Developed skills and lines of research
Annamaria Bevivino graduated in Biological Sciences from the University of Rome La Sapienza with 110/110 cum laude[1] . She has been an ENEA researcher since 1989. Since 2018, she has held the position of BIOAG-SOQUAS laboratory manager of the ENEA Sustainability Department. She is University lecturer in Agricultural and Food Microbiology, Master’s Degree Course in Food Science and Human Nutrition, Rome Biomedical Campus University.
Her research activities over the years have covered the following thematic areas: microbial ecology; study of opportunistic pathogens in the environment and in cystic fibrosis; taxonomy, epidemiology, ecology and virulence of opportunistic pathogen strains such as Burkholderia cepacia complex and Pseudomonas aeruginosa; microbial biofim; and pathogen-host interactions. Her current research focuses on investigating the airway microbiome in patients with cystic fibrosis who have severe decline in lung function, hoping to highlight an opportunity for microbiome-based personalized therapy. H-index (Google scholar) of 29.
Projects funded by FFC Ricerca as Principal Investigator or as Research Manager
FFC#19/2017
A longitudinal metagenomic analysis to uncover microbial signatures of CF lung disease: unravelling host-microbial community interactions in humans and animal models
FFC#14/2015
Investigating the airway microbiome in cystic fibrosis patients with a severe decline in lung function: an opportunity for a personalized microbiome-based therapy
FFC#10/2014
Investigating the airway microbiome in cystic fibrosis patients with a severe decline in lung function: an opportunity for a personalized microbiomebased therapy
FFC#8/2012
nvestigation of cystic fibrosis airway microbiome in patients showing a severe decline in lung function and not responding to conventional antimicrobial therapy
FFC #7/2008
Burkholderia cenocepacia pathogenicity: synergistic interactions with Pseudomonas aeruginosa and adaptation to CF host
FFC#7/2006
Influence of Pseudomonas aeruginosa and CF host on Burkholderia cenocepacia pathogenicity
FFC#11/2004
Evaluation of the pathogenicity of environmental and clinical isolates of Burkholderia cepacia complex alone and in the presence of Pseudomonas aeruginosa
Publications from FFC Research projects
Chiarini L, Bevivino A, Dalmastri C et al., Burkholderia Cepacia complex species: health hazards and biotechnological potential, Trends in Microbiology, 2006, 14(6):277-86
Pirone L. Bragonzi A, Farcomeni A et al., Burkholderia cenocepacia strains isolated from cystic fibrosis patients are apparently more invasive and more virulent than rhizosphere strains, Enviromental Microbiology, 2008, 10(10):2773-84
Bevivino A, Pirone L, Pilkington R et al., Interaction of environmental Burkholderia cenocepacia strains with cystic fibrosis and non-cystic fibrosis bronchial epithelial cells in vitro, Microbiology, 2012, 158(Pt 5):1325-33
Bragonzi A, Farulla I, Paroni M et al., Modelling co-infection of the cystic fibrosis lung by Pseudomonas aeruginosa and Burkholderia cenocepacia reveals influence on biofilm formation and host response, PLoS ONE, 2012, 7(12):e52330
Paganin P, Fiscarelli EV, Tuccio V et al., Changes in cystic fibrosis airway microbial community associated with a severe decline in lung function, PLoS ONE, 2015, 10(4):e0124348
Annamaria Bevivino, Giovanni Bacci, Pavel Drevinek, et al. Deciphering the Ecology of Cystic Fibrosis Bacterial Communities: Towards Systems-Level Integration.
2019. Trends Mol Med , 25 (12), 1110-1122
Bacci G, Mengoni A, Fiscarelli E, et al. A Different Microbiome Gene Repertoire in the Airways of Cystic Fibrosis Patients with Severe Lung Disease. Int J Mol Sci. 2017;18(8):1654. Published 2017 Jul 29. doi:10.3390/ijms18081654
Bragonzi A, Paroni M, Pirone L, Coladarci I, Ascenzioni F, Bevivino A. Environmental Burkholderia cenocepacia Strain Enhances Fitness by Serial Passages during Long-Term Chronic Airways Infection in Mice. Int J Mol Sci. 2017;18(11):2417. Published 2017 Nov 14. doi:10.3390/ijms18112417
Paganin P, Fiscarelli EV, Tuccio V, et al. Changes in cystic fibrosis airway microbial community associated with a severe decline in lung function. PLoS One. 2015;10(4):e0124348. Published 2015 Apr 21. doi:10.1371/journal.pone.0124348