The goal of the project is to understand if the radiation-free Magnetic Resonance Imaging (multivolume MRI) can diagnose changes in the structure of the lung of individuals with CF treated with CFTR modulators. The benefit of the new modulating drugs is usually investigated through respiratory function tests (standard spirometry and forced expiratory flow measurements), which however do not indicate whether the functional improvement is also accompanied by a recovery of the lung structure, in particular of the bronchi, which are the sites of bronchiectasis. The researchers intend to investigate whether all that occurs, by relating the information provided by multivolume Nuclear Magnetic Resonance with those obtained from spirometry and other lung function tests, such as the Lung Clearance Index; they will perform a retrospective study involving people with CF from the Adult CF Center of Milan. The ultimate goal is to implement and validate this new magnetic resonance technique as diagnostically sensitive and ionizing radiations-free.