NETWORK PROJECTS

Network Projects

NETWORK PROJECTS

Below are listed all research projects funded by the Foundation from 2002 to today, divided by scientific area. The FFC Ricerca Scientific Committee selects them according to two fundamental goals: improving the available treatments to increase the quality of life of pwCF; finding a definitive cure for CF acting on the basic defect.

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AREA 1 Therapies to correct the underlying defect

GMRF#1/2026

Exploring the role of PKD1 in promoting CFTR stability and function at the cell surface
€ 105.000 funds raised
0%
€ 105.000
Goal

AREA 1 Therapies to correct the underlying defect

FFC#1/2026

Mapping proteins regulating CFTR mRNA stability to identify new therapeutic targets for nonsense mutations
€ 209.890 funds raised
0%
€ 209.890
Goal

AREA 2 Personalized therapies

FFC#2/2026

Evaluating the potential of phosphodiesterase inhibitors to enhance the efficacy of CFTR modulators and support personalized therapeutic approaches
€ 210.000 funds raised
0%
€ 210.000
Goal

AREA 3 Bronchopulmonary infection

FFC#3/2026

Developing an innovative technology to deliver antibiotics with high specificity to cells infected with Mab
€ 210.000 funds raised
0%
€ 210.000
Goal

AREA 3 Bronchopulmonary infection

FFC#4/2026

Inhibiting DksA, a protein that is key to the bacterium’s survival within the host, to develop new therapies to be used alongside CFTR modulators
€ 208.950 funds raised
0%
€ 208.950
Goal

AREA 3 Bronchopulmonary infection

FFC#5/2026

Formulation of a vaccine against Pseudomonas aeruginosa
€ 210.000 funds raised
0%
€ 210.000
Goal

AREA 4 Lung inflammation

FFC#6/2026

Studying bone marrow to find out whether chronic inflammation is caused by a programming defect in the immune system
€ 210.000 funds raised
0%
€ 210.000
Goal

AREA 5 Clinical and Epidemiological research

FFC#7/2026

Investigating the effects of CFTR modulators and the role of the CFTR protein in placental development
€ 100.065 funds raised
0%
€ 100.065
Goal

AREA 3 Bronchopulmonary infection

GMSG#1/2025

Developing PNAs to Block Essential Bacterial Genes and Create New Antimicrobial Therapies
€ 177.450 funds raised
0%
€ 177.450
Goal