NETWORK PROJECTS

Network Projects

NETWORK PROJECTS

Below are listed all research projects funded by the Foundation from 2002 to today, divided by scientific area. The FFC Ricerca Scientific Committee selects them according to two fundamental goals: improving the available treatments to increase the quality of life of pwCF; finding a definitive cure for CF acting on the basic defect.

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AREA 3 Bronchopulmonary infection

GMSG#1/2025

Developing PNAs to Block Essential Bacterial Genes and Create New Antimicrobial Therapies

€ 177.450 funds raised

€ 177.450
Goal

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AREA 1 Therapies to correct the underlying defect

FFC#1/2025

Understanding the process of epithelial-mesenchymal transition to preserve tissue function and reduce long-term complications (e.g. cancer)

€ 209.897 funds raised

€ 209.897
Goal

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AREA 1 Therapies to correct the underlying defect

FFC#2/2025

Developing RNA-targeted therapies to regulate gene expression and restore CFTR synthesis

€ 173.250 funds raised

€ 173.250
Goal

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AREA 1 Therapies to correct the underlying defect

FFC#3/2025

Developing Compact Base Editors for R553X and Pulmonary-Targeted Lipid Nanoparticles

€ 209.998 funds raised

€ 209.998
Goal

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AREA 1 Therapies to correct the underlying defect

FFC#4/2025

Exploring Small Molecules and Anti-Inflammatory Strategies to Restore CFTR function

€ 210.000 funds raised

€ 210.000
Goal

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AREA 1 Therapies to correct the underlying defect

FFC#5/2025

Analysis of PKD1 to Enhance the Correction of CFTR Mutations by Modulators

€ 135.975 funds raised

€ 135.975
Goal

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AREA 1 Therapies to correct the underlying defect

FFC#6/2025

Evaluating the Effectiveness of a Combined Approach to Enhance CFTR Gating Mutations and Combat Lung Pathogens

€ 136.500 funds raised

€ 136.500
Goal

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AREA 3 Bronchopulmonary infection

FFC#7/2025

In vitro and in vivo validation of aztreopine and development of novel antibiotic-zinc conjugates against Pseudomonas aeruginosa

€ 105.000 funds raised

€ 105.000
Goal

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AREA 3 Bronchopulmonary infection

FFC#8/2025

Optimization of bioactive liposomes containing antibiotics for a dual effect, antimicrobial action against the pathogen and anti-inflammatory action on the host

€ 136.500 funds raised

€ 136.500
Goal

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